If I were simply cataloging a bunch of books, I’d use a dedicated database like Delicious Library. You get the advantages of a database, plus a certain amount of specialized bibliographic knowledge built into the system.
If I wanted, though, to study a collection — to understand its contents, the way it was put together, the books omitted, its use and influence — I’d certainly use Tinderbox. That would be true as well if “the collection” were pretty much the same as “the literature” or “the current state of knowledge.”
And if I were simply planning to use some of these books as a resource for composing a number of essays or articles or new books, I might want to catalog them in a database but I’d certainly want extracts from the catalog in Tinderbox to help plan further research and to help guide the early stages of composition.